Article

Pharmacogenetics of the Human MDR1 Multidrug Transporter.

2004-03-01

Abstract excerpt

This review discusses the regulatory role of the human MDR1 multidrug transporter in the traffic of drugs and xenobiotics into the body as well as into certain organs and tissues (e.g. brain, germ cells, fetus). It also explores the relevance of single nucleotide polymorphisms (SNPs) within the MDR1 gene with respect to variations in MDR1 protein expression and function. In silico methods of SNP identification in...

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Literature Corpus work: 13c714c8-14dc-5774-934a-c9136b491c2e
DOI: 10.2174/1570160043476097

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