Article
N-methyl-D-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels.
Schizophrenia research - 1 Jun 2006
Martucci Livia, Wong Albert H C, De Luca Vincenzo, Likhodi Olga, Wong Gregory W H, King Nicole, Kennedy James L
Abstract excerpt
The NR2B protein is a critical structural and functional subunit of the NMDA glutamate receptor. The glutamate neurotransmitter system has been implicated in psychosis and schizophrenia, and so we looked for genetic association and measured gene expression in human DNA and brain samples, respectively, of the GRIN2B gene that codes for the NR2B protein. We tested three genetic polymorphisms: G-200T (5'UTR), A5806C...
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