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Article

CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain.

Nature structural & molecular biology - 1 May 2005

Kim Jae-Hwan, Cho Eun-Jung, Kim Seong-Tae, Youn Hong-Duk

Abstract excerpt

Histone acetyltransferase coactivators bind to acetylated histones through their bromodomains and catalyze the acetylation of histone H3 and H4 tails for transcriptional activation. C-terminal binding protein (CtBP) serves as a transcriptional corepressor by recruiting histone deacetylases. However, the precise mechanism by which CtBP represses transcription has not been determined. In this study we found that...

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PMID: 15834423
DOI: 10.1038/nsmb924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain.PMID 15834423Read ↗

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