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Article

p300/CBP proteins: HATs for transcriptional bridges and scaffolds

1 Jul 2001

Abstract excerpt

p300/CBP transcriptional co-activator proteins play a central role in co-ordinating and integrating multiple signal-dependent events with the transcription apparatus, allowing the appropriate level of gene activity to occur in response to diverse physiological cues that influence, for example, proliferation, differentiation and apoptosis. p300/CBP activity can be under aberrant control in human disease,...

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PMID: 11559745
DOI: 10.1242/jcs.114.13.2363

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