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Article

Life and death of transcriptional co-activator p300

1 Aug 2011

Abstract excerpt

Transcriptional co-activator p300, which contains an intrinsic histone acetyltransferase activity, is required for an array of important cellular processes. Tight control of p300 function is critical to ensure precise histone acetylation and gene activation. Dysregulation of p300 has been implicated in many types of diseases and numerous studies have examined the functional requirement of p300 to act as a...

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PMID: 21730760
DOI: 10.4161/epi.6.8.16065

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