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Article

Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration.

Molecular and cellular biology - 1 May 2005

Woods Alison J, Kantidakis Theodoros, Sabe Hisataka, Critchley David R, Norman Jim C

Abstract excerpt

We have previously identified poly(A)-binding protein 1 (PABP1) as a ligand for paxillin and shown that the paxillin-PABP1 complex undergoes nucleocytoplasmic shuttling. By targeting the paxillin-binding subdomain sequences in PABP1, we have generated mutants of PABP1 that do not bind to cellular paxillin. Here we report that paxillin association is necessary for efficient nuclear export of PABP1 and that RNA...

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Identifiers

PMID: 15831480
DOI: 10.1128/MCB.25.9.3763-3773.2005
PMCID: PMC1084280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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