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Article

Paxillin genes and actomyosin contractility regulate myotome morphogenesis in zebrafish.

Developmental biology - 1 May 2017

Jacob Andrew E, Amack Jeffrey D, Turner Christopher E

Abstract excerpt

Paxillin (Pxn) is a key adapter protein and signaling regulator at sites of cell-extracellular matrix (ECM) adhesion. Here, we investigated the role of Pxn during vertebrate development using the zebrafish embryo as a model system. We have characterized two Pxn genes, pxna and pxnb, in zebrafish that are maternally supplied and expressed in multiple tissues. Gene editing and antisense gene knockdown approaches...

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Identifiers

PMID: 28315297
DOI: 10.1016/j.ydbio.2017.03.012
PMCID: PMC5495106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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