Article
A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27.
Journal of medical genetics - 1 Oct 2004
Shen H, Zhang Y-Y, Long J-R, Xu F-H, Liu Y-Z, Xiao P, Zhao L-J, Xiong D-H, Liu Y-J, Dvornyk V, Rocha-Sanchez S, Liu P-Y, Li J-L, Conway T, Davies K M, Recker R R, Deng H-W
Abstract excerpt
BACKGROUND: Osteoporosis is a major public health problem, mainly quantified by low bone mineral density (BMD). The majority of BMD variation is determined by genetic effects. A pilot whole genome linkage scan (WGS) was previously reported in 53 white pedigrees with 630 subjects. Several genomic...
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