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Article

APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2005

Tranah Gregory J, Giovannucci Edward, Ma Jing, Fuchs Charles, Hunter David J

Abstract excerpt

Mutation of the adenomatous polyposis coli (APC) tumor suppressor gene is an important initiating factor in the early stages of the adenoma-carcinoma sequence. The aim of this study was to investigate the two most common APC variants (Asp1822Val and Gly2502Ser) and their association with colorectal cancer and adenoma and whether these relationships are influenced by dietary and lifestyle factors. We analyzed 556...

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Identifiers

PMID: 15824157
DOI: 10.1158/1055-9965.EPI-04-0687

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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