Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas.

BMC cancer - 17 Mar 2006

Sarebø Mona, Skjelbred Camilla F, Breistein Rebecca, Lothe Inger Marie B, Hagen Per Chr, Bock Gunter, Hansteen Inger-Lise, Kure Elin H

Abstract excerpt

BACKGROUND: The association between colorectal cancer (CRC) and smoking has not been consistent. Incomplete smoking history and association to a specific subset of CRC tumors have been proposed as explanations. The adenomatous polyposis coli (APC) gene has been reported to have a "gatekeeper" function in the colonic mucosa. METHODS: To evaluate the hypothesis that cigarette smoking is associated with adenoma and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Colorectal Neoplasms

Share to DNA Mutational Analysis

Share to DNA, Neoplasm

Share to Genes, APC

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 16545110
DOI: 10.1186/1471-2407-6-71
PMCID: PMC1475604

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas.PMID 16545110Read ↗

APC and KRAS mutations in distal colorectal polyps are related to smoking habits in men: results of a cross-sectional study.Semantic proximity Read ↗

Dietary factors and the occurrence of truncating APC mutations in sporadic colon carcinomas: a Dutch population-based study.Semantic proximity Read ↗

The impact of APC polymorphisms on the transition from polyps to colorectal cancer (CRC).Semantic proximity Read ↗

Cigarette smoking and genetic alterations in sporadic colon carcinomas.Semantic proximity Read ↗

The relationship between smoking exposure and p53 overexpression in colorectal cancer.Semantic proximity Read ↗

Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps.Semantic proximity Read ↗

Cigarette Smoking and Colorectal Cancer: APC Mutations, hMLH1 Expression, and GSTM1 and GSTT1 PolymorphismsSemantic proximity Read ↗

Dietary factors and truncating APC mutations in sporadic colorectal adenomas.Semantic proximity Read ↗

Increased frequency of p53 mutation in sporadic colorectal cancer from cigarette smokers.Semantic proximity Read ↗

APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenoma.Semantic proximity Read ↗

Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk.Semantic proximity Read ↗

APC gene 3'UTR SNPs and interactions with environmental factors are correlated with risk of colorectal cancer in Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.