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Article

Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma.

British journal of cancer - 27 Mar 2006

Schernhammer E S, Tranah G J, Giovannucci E, Chan A T, Ma J, Colditz G A, Hunter D J, Willett W C, Fuchs C S

Abstract excerpt

Cyclin D1 (CCND1) plays a key role in cell cycle control, particularly in the transition from G1 to S phase, which is regulated by cyclin-dependent kinases. A common adenine to guanine polymorphism (A870G) in the CCND1 gene has been associated with a longer-life protein and an increased risk of colorectal cancer and adenoma in some studies. Among subjects with hereditary nonpolyposis colorectal cancer, the A870G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16495921
DOI: 10.1038/sj.bjc.6603007
PMCID: PMC2361367

Genes

CCND1
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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