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Article

Presence of a TA haplotype in the APC gene containing the common 1822 polymorphism and colorectal adenoma.

Cancer research - 15 Jul 2008

Egan Jan B, Jacobs Elizabeth T, Martínez María Elena, Gerner Eugene W, Jurutka Peter W, Thompson Patricia A

Abstract excerpt

Acquired or inherited mutations in the adenomatous polyposis coli (APC) tumor suppressor gene are causally linked to colorectal cancer. Given the significance of APC in colorectal cancer, we investigated the association between common single-nucleotide polymorphisms (SNP) in the APC gene and the odds of developing metachronous colorectal adenomas as a surrogate measure of colorectal cancer risk. Coding SNPs at...

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Source

Identifiers

PMID: 18632657
DOI: 10.1158/0008-5472.CAN-08-1084

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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