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Article

The impact of APC polymorphisms on the transition from polyps to colorectal cancer (CRC).

Gene - 25 May 2020

Sa Rina, Song Huali, Wei Meihua, Su Hailong, Hong Yao, Zhou Lulu, Bai Yunfei

Abstract excerpt

OBJECTIVE: The purpose of this study was to investigate the function of APC polymorphisms (D1822V and E1317Q) on the transition from polyps to colorectal cancer (CRC). METHODS: 259 patients with polyps were included in the study. APC polymorphisms were genotyped via polymerase chain reaction (PCR) and subsequent sequencing. χ2 test was performed to analyze the relationship of APC polymorphisms or CRC occurrence...

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Identifiers

PMID: 32087273
DOI: 10.1016/j.gene.2020.144486

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