Mutations and amplification of oncogenes in endometrial cancer.

Abstract excerpt

Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 tumors were examined using PCR-based fluorescent DNA technology. Amplification of the three oncogenes and the mutation of K-ras were correlated with age, tumor size,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA, Neoplasm
• Share to DNA Primers
• Share to Gene Amplification