Article
Detection of K-ras mutations in cancerous lesions of human endometrium.
European journal of gynaecological oncology - 1 Jan 1997
Semczuk A, Berbéc H, Kostuch M, Kotarski J, Wojcierowski J
Abstract excerpt
The many genetic changes associated with human carcinogenesis include the activation and/or inactivation of various genes. Polymerase-chain reaction and single-strand conformation polymorphism analysis [PCR-SSCP] was used to detect alterations at exon 1 of the K-ras gene in 20 lesions of human endometrium. Six cases of endometrial hyperplasia, 13 of endometrial carcinoma and one of endometrial metastasis of...
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