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Article

Micronuclei assay by laser scanning cytometry

1 Jan 2001

Abstract excerpt

BACKGROUND: The micronuclei (MN) assay is used to assess the chromosomal/mitotic spindle damage induced by ionizing radiation or mutagenic agents in vivo or in vitro. Because visual scoring of MN is cumbersome semi-automatic procedures that relay either on flow cytometry or image analysis were developed: both offer some advantages but also have shortcomings. METHODS: In the present study laser scanning cytometer...

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PMID: 11598943
DOI: 10.1002/1097-0320(20010901)45:1<19::aid-cyto1140>3.0.co;2-g

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