Micronuclei and mitotic index in B-, T4- and T8-cells treated with mitomycin C and gamma-irradiation.

doi:10.1016/0027-5107(94)90046-9

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Article

Micronuclei and mitotic index in B-, T4- and T8-cells treated with mitomycin C and gamma-irradiation.

Mutation research - 1 Aug 1994

Holmén A, Karlsson A, Bratt I, Högstedt B

Abstract excerpt

Lymphocytes were treated in vitro with mitomycin C and gamma-radiation at different doses (0-250 nmol/l and 0-2 Gy, respectively). After incubation in RPMI 1640 medium and stimulation with phytohemagglutinin for 72 h, the lymphocyte subgroups T4 (CD4), T8 (CD8) and B (CD19) were separated by an i...

Topics

B-Lymphocytes
CD4-Positive T-Lymphocytes
Cells, Cultured
Gamma Rays
Humans
Lymphocyte Subsets
Micronucleus Tests
Mitomycin
Mitotic Index
Mutation
Phytohemagglutinins
T-Lymphocytes

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