Article
Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline.
Nucleic acids research - 1 Jan 2005
Kalmykova Alla I, Klenov Mikhail S, Gvozdev Vladimir A
Abstract excerpt
Proteins of the Argonaute family have been identified as key components of RNA interference (RNAi) pathway. RNAi-related mechanisms are implicated in the regulation of gene expression and repression of transposable elements in eukaryotes. The piwi gene encoding protein of the Drosophila Argonaute family was shown to be required for the germ stem cells maintenance. Here, we show that piwi is involved in silencing...
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