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Article

The RNA interference proteins and vasa locus are involved in the silencing of retrotransposons in the female germline of Drosophila melanogaster.

RNA biology - 1 May 2004

Vagin Vasily V, Klenov Mikhail S, Kalmykova Alla I, Stolyarenko Anastasia D, Kotelnikov Roman N, Gvozdev Vladimir A

Abstract excerpt

RNA interference (RNAi) is considered as a defense against expansion of transposable elements. The proteins related to RNA helicase and Argonaute families are involved in RNAi process in different organisms. It was shown that Argonaute AUBERGINE and putative RNA helicase SPINDLE-E proteins were essential for RNAi in Drosophila. Here, we describe the role of aubergine (aub) and spindle-E (spn-E) genes in the...

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PMID: 17194939

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