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Article

Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene.

Cancer letters - 28 Apr 2005

Keshava Channa, Divi Rao L, Whipkey Diana L, Frye Bonnie L, McCanlies Erin, Kuo Maryanne, Poirier Miriam C, Weston Ainsley

Abstract excerpt

Inter-individual variation in formation of carcinogen-DNA adducts and induction of cytochrome P450 genes was measured in 23 cultured normal human mammary epithelial cell (NHMEC) strains established from reduction mammoplasty tissue. Semi-confluent cells were exposed to 4 microM benzo[a]pyrene (BP) for 12 h and BP-DNA adduct levels were measured by chemiluminescence immunoassay using antiserum elicited against DNA...

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Source

Identifiers

PMID: 15808407
DOI: 10.1016/j.canlet.2004.08.038

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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