Article
Benzo[a]pyrene-induced DNA-protein crosslinks in cultured human lymphocytes and the role of the GSTM1 and GSTT1 genotypes.
Journal of Korean medical science - 1 Jun 2002
Park Hye-Sook, Ha Eun-Hee, Lee Kwan-Hee, Hong Yun-Chul
Abstract excerpt
We investigated the influence of glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) polymorphisms upon DNA-protein crosslinks (DPC) induced by benzo[a]pyrene (B[a]P) in cultured human lymphocytes. Lymphocyte samples were collected from 30 healthy nonsmoking hospital administrative workers. DPC was detected with KCl-SDS assay and the distributions of GSTM1 and GSTT1 were determined by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
