Article
Molecular cloning and polymorphism analysis of the prion protein gene in Tan sheep of Ningxia, China.
Gene - 10 Oct 2011
Xu Lihua, Zhang Zhuming, Zhou Xiangmei, Yin Xiaomin, Yang Lifeng, Zhao Deming
Abstract excerpt
The resistance or susceptibility of sheep to scrapie is associated with polymorphisms of the prion protein gene (PRNP), particularly, single nucleotide polymorphisms (SNPs) in amino acid positions 136, 154 and 171. The prion protein (PrP) gene sequence and the deduced amino acid alignment of prion protein in Tan sheep, a local Chinese sheep breed traditionally raised in Ningxia, northwestern China, were...
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