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Article

Novel polymorphisms in the caprine PrP gene: a codon 142 mutation associated with scrapie incubation period.

The Journal of general virology - 1 Nov 1996

Goldmann W, Martin T, Foster J, Hughes S, Smith G, Hughes K, Dawson M, Hunter N

Abstract excerpt

Age at disease onset and rate of progression of transmissible spongiform encephalopathies in man, sheep and mice are modulated by the host genome, in particular by the PrP gene and its allelic forms. Analysis of the caprine PrP gene revealed several different alleles. Four PrP protein variants were found, three of which were goat specific with single amino acid changes at codons 142, 143 and 240. The fourth was...

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Identifiers

PMID: 8922485
DOI: 10.1099/0022-1317-77-11-2885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel polymorphisms in the caprine PrP gene: a codon 142 mutation associated with scrapie incubation period.PMID 8922485Read ↗

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