Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent.

Brain research - 8 Apr 2005

Schauwecker Paula Elyse

Abstract excerpt

Previously, we had reported that hippocampal susceptibility to the neurotoxic effects of excitotoxin administration is strain dependent [Schauwecker and Steward, Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 4103]. However, it has been unclear whether strain-related gene products may play a similar role in providing protection against drugs that produce striatal lesions. The present series of experiments sought to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corpus Striatum
Share to Excitatory Amino Acid Agonists
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Nerve Degeneration

Share to Species Specificity

Source

Identifiers

PMID: 15804432
DOI: 10.1016/j.brainres.2005.01.067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent.PMID 15804432Read ↗

Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains.Semantic proximity Read ↗

Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions.Semantic proximity Read ↗

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.Semantic proximity Read ↗

Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury.Semantic proximity Read ↗

Mice transgenic for the Huntington's disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity.Semantic proximity Read ↗

Strain and colony differences in the neurotoxic sequelae of MK-801 visualized with the amino-cupric-silver method.Semantic proximity Read ↗

Systems analysis of genetic variation in MPTP neurotoxicity in mice.Semantic proximity Read ↗

Influence of mouse genotype on responses of central biogenic amines to alcohol intoxication and aging.Semantic proximity Read ↗

Influence of Age and Strain on Striatal Dopamine Loss in a Genetic Mouse Model of Lesch‐Nyhan DiseaseSemantic proximity Read ↗

Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains.Semantic proximity Read ↗

Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death.Semantic proximity Read ↗

iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.