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Article

iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion.

Acta neurochirurgica - 1 Apr 2012

Günther Mattias, Al Nimer Faiez, Gahm Caroline, Piehl Fredrik, Mathiesen Tiit

Abstract excerpt

BACKGROUND: Nitric oxide is a key mediator of post-traumatic inflammation in the brain. We examined the expressions of iNOS, nNOS, and eNOS in inbred DA and PVGa rat strains where DA is susceptible to autoimmune neuroinflammation and PVGa-resistant. METHODS: Parietal contusions using a weight drop model were produced in five rats per genotype. After 24 h, the brains were removed and analyzed using a range of...

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PMID: 22362050
DOI: 10.1007/s00701-012-1297-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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