Article
Frequency of the CCR5-Delta32 mutant allele is not increased in Belgian hepatitis C virus-infected patients.
Viral immunology - 1 Jan 2005
Thoelen Inge, Verbeeck Jannick, Wollants Elke, Maes Piet, Robaeys Geert, Matheï Cathy, Buntinx Frank, Nevens Frederik, Van Ranst Marc
Abstract excerpt
A 32-base pair deletion in the CC-chemokine receptor 5 gene (CCR5), associated with resistance to human immunodeficiency virus type 1 (HIV-1) infection, has recently been suggested to act as an adverse host factor in hepatitis C virus (HCV) infection. To examine this hypothesis, we determined the CCR5-Delta32 allele frequency by polymerase chain reaction in a Belgian cohort of 163 HCV-infected patients and 310...
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