Article
CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection.
Genes and immunity - 1 Jan 2000
Suppiah V, Armstrong N J, O'Connor K S, Berg T, Weltman M, Abate M L, Spengler U, Bassendine M, Dore G J, Irving W L, Powell E, Nattermann J, Mueller T, Riordan S, Stewart G J, George J, Booth D R, Ahlenstiel G
Abstract excerpt
IL28B polymorphisms strongly predict spontaneous and treatment-induced clearance of hepatitis C virus (HCV) infection. A recent study proposed a 32-base pair deletion in the CC-chemokine receptor 5 (CCR5) gene (CCR5-Δ32) interacting with the IL28B polymorphisms to influence spontaneous HCV clearance. The aim of this study was to clarify the role of CCR5-Δ32 in treatment-induced clearance of chronic hepatitis C...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
