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Article

Estrogen and progesterone-related gene variants and colorectal cancer risk in women.

BMC medical genetics - 31 May 2011

Lin Jennifer H, Manson JoAnn E, Kraft Peter, Cochrane Barbara B, Gunter Marc J, Chlebowski Rowan T, Zhang Shumin M

Abstract excerpt

BACKGROUND: Observational studies and randomized trials have suggested that estrogens and/or progesterone may lower the risk for colorectal cancer. Inherited variation in the sex-hormone genes may be one mechanism by which sex hormones affect colorectal cancer, although data are limited. METHOD: We conducted a comprehensive evaluation of single nucleotide polymorphisms (SNPs) in genes encoding 3 hormone receptors...

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Topics

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Share to Androgens
Share to Aromatase
Share to Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxysteroid Dehydrogenases

Share to Postmenopause

Share to Progesterone

Share to Receptors, Progesterone

Share to Steroid 17-alpha-Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 21627810
DOI: 10.1186/1471-2350-12-78
PMCID: PMC3125237

Genes

ESR1
ESR2
PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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