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Article

Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes.

Carcinogenesis - 1 May 2010

Yang Hannah P, Gonzalez Bosquet Jesus, Li Qizhai, Platz Elizabeth A, Brinton Louise A, Sherman Mark E, Lacey James V, Gaudet Mia M, Burdette Laurie A, Figueroa Jonine D, Ciampa Julia G, Lissowska Jolanta, Peplonska Beata, Chanock Stephen J, Garcia-Closas Montserrat

Abstract excerpt

BACKGROUND: Estrogen plays a major role in endometrial carcinogenesis, suggesting that common variants of genes in the sex hormone metabolic pathway may be related to endometrial cancer risk. In support of this view, variants in CYP19A1 [cytochrome P450 (CYP), family 19, subfamily A, polypeptide...

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Identifiers

PMID: 20053928
DOI: 10.1093/carcin/bgp328
PMCID: PMC2864407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20053928-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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