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Article

The prognostic role of microsatellite instability, codon-specific KRAS, and BRAF mutations in colon cancer.

Journal of surgical oncology - 1 Sept 2014

Lin Chun-Chi, Lin Jen-Kou, Lin Tzu-Chen, Chen Wei-Shone, Yang Shung-Haur, Wang Huann-Sheng, Lan Yuan-Tzu, Jiang Jeng-Kai, Yang Muh-Hwa, Chang Shih-Ching

Abstract excerpt

BACKGROUND: This study aimed to establish a correlation between MSI, KRAS mutations, and BRAF(V600E) in colon cancer and to investigate the prognostic effect. METHODS: Colon cancer patients who underwent surgical intervention were enrolled. MSI status was identified by genotyping, and the mutational statuses of KRAS and BRAF were determined by MassARRAY, targeting 22 mutations. The clinicopathological differences...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24964758
DOI: 10.1002/jso.23675

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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