Article
Low-level microsatellite instability in most colorectal carcinomas.
Cancer research - 15 Feb 2002
Laiho Päivi, Launonen Virpi, Lahermo Päivi, Esteller Manel, Guo Mingzhou, Herman James G, Mecklin Jukka-Pekka, Järvinen Heikki, Sistonen Pertti, Kim Kyoung-Mee, Shibata Darryl, Houlston Richard S, Aaltonen Lauri A
Abstract excerpt
Twelve to 16% of colorectal cancers (CRCs) display a high degree of microsatellite instability (MSI-H), whereas most are believed to be microsatellite stable (MSS). The existence of a low degree of instability (MSI-L) group has also been proposed. By using the Bethesda panel of microsatellite markers, the microsatellite instability (MSI) status of CRCs can be determined. This set is recommended to distinguish...
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