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Article

Structure of Adeno-Associated Virus Type 4

28 Mar 2005

Abstract excerpt

Adeno-associated virus (AAV) is a member of the Parvoviridae, belonging to the Dependovirus genus. Currently, several distinct isolates of AAV are in development for use in human gene therapy applications due to their ability to transduce different target cells. The need to manipulate AAV capsids for specific tissue delivery has generated interest in understanding their capsid structures. The structure of AAV...

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PMID: 15795290
DOI: 10.1128/jvi.79.8.5047-5058.2005

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