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Adeno-associated virus (AAV) cell entry: structural insights

25 Oct 2021

Abstract excerpt

Adeno-associated virus (AAV) is the leading vector in emerging treatments of inherited diseases. Higher transduction efficiencies and cellular specificity are required for broader clinical application, motivating investigations of virus-host molecular interactions during cell entry. High-throughput methods are identifying host proteins more comprehensively, with subsequent molecular studies revealing...

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PMID: 34711462
DOI: 10.1016/j.tim.2021.09.005

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