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Article

The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle.

The Journal of biological chemistry - 10 Jun 2005

Briknarová Klára, Nasertorabi Fariborz, Havert Marnie L, Eggleston Ericka, Hoyt David W, Li Chenglong, Olson Arthur J, Vuori Kristiina, Ely Kathryn R

Abstract excerpt

p130(cas) (Crk-associated substrate) is a docking protein that is involved in assembly of focal adhesions and concomitant cellular signaling. It plays a role in physiological regulation of cell adhesion, migration, survival, and proliferation, as well as in oncogenic transformation. The molecule consists of multiple protein-protein interaction motifs, including a serine-rich region that is positioned between Crk...

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PMID: 15795225
DOI: 10.1074/jbc.M501258200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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