Article
NXT2 is required for embryonic heart development in zebrafish.
BMC developmental biology - 24 Mar 2005
Huang Haigen, Zhang Bo, Hartenstein Parvana A, Chen Jau-nian, Lin Shuo
Abstract excerpt
BACKGROUND: NXT2 is a member of NXT family proteins that are generally involved in exporting nuclear RNA in eukaryotic cells. It is not known if NXT2 has any function in specific biological processes. RESULTS: A zebrafish mutant exhibiting specific heart defects during embryogenesis was generated by animal cloning-mediated retroviral insertions. Molecular analysis indicated that the mutant phenotype was caused by...
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