Epigenetic analysis of <i>HIC1</i> , <i>CASP8</i> , <i>FLIP</i> , <i>TSP1</i> , <i>DCR1</i> , <i>DCR2</i> , <i>DR4</i> , <i>DR5</i> , KvDMR1, <i>H19</i> and preferential 11p15.5 maternal-allele loss in von Hippel-Lindau and sporadic phaeochromocytomas

Abstract excerpt

Phaeochromocytoma is a neural-crest-derived tumour that may be a feature of several familial cancer syndromes including von Hippel-Lindau (VHL) disease, multiple endocrine neoplasia type 2 (MEN 2), neurofibromatosis type 1 (NF1) and germline succinate dehydrogenase subunit (SDHB and SDHD) mutations. However the somatic genetic and epigenetic events that occur in phaeochromocytoma tumourigenesis are not well...

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