Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter Methylation Status of Ras-Association Domain Family Member in Pheochromocytoma

19 Feb 2015

Abstract excerpt

Pheochromocytomas (PCCs) are rare neuroendocrine tumors that arise from the medulla of the adrenal gland or the sympathetic ganglia and are characterized by the secretion of catecholamines. In 30-40% of patients, PCCs are genetically determined by susceptibility genes as various as RET, VHL, and NF1. We have analyzed the Ras-association domain family members (RASSFs) in PCCs regarding their inactivating promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Cancer, Hypoxia, and Metabolism
Share to Hormonal Regulation and Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25750636
DOI: 10.3389/fendo.2015.00021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter Methylation Status of Ras-Association Domain Family Member in PheochromocytomaPMID 25750636Read ↗

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastomaSemantic proximity Read ↗

Circulating Tumor DNA (ctDNA) Methylation Quantification As Diagnostic Biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs)Semantic proximity Read ↗

Genetic aspects of pheochromocytoma.Semantic proximity Read ↗

Aberrant promoter methylation, expression and function of RASSF1A gene in a series of Italian parathyroid tumorsSemantic proximity Read ↗

Methylation of the p16INK4A promoter is associated with malignant behavior in abdominal extra-adrenal paragangliomas but not pheochromocytomas.Semantic proximity Read ↗

Association of Epigenetic Inactivation of RASSF1A with Poor Outcome in Human NeuroblastomaSemantic proximity Read ↗

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.Semantic proximity Read ↗

Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas.Semantic proximity Read ↗

Domain landscapes of somatic NF1 mutations in pheochromocytoma and paraganglioma.Semantic proximity Read ↗

Global and Regional CpG Methylation in Pheochromocytomas and Abdominal Paragangliomas: Association to Malignant BehaviorSemantic proximity Read ↗

Global DNA methylation patterns through an array-based approach in small intestinal neuroendocrine tumorsSemantic proximity Read ↗

Genetic aspects of pheochromocytoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.