Article
Potentiation of ATP-induced Ca2+ mobilisation in human retinal pigment epithelial cells.
Experimental eye research - 1 Apr 2005
Collison David J, Tovell Victoria E, Coombes Laura J, Duncan George, Sanderson Julie
Abstract excerpt
Interaction of signalling pathways directs the functional output of many cells. This study investigated the consequences of activating adenosine and adrenergic receptors on ATP-induced Ca2+ responses in human retinal pigment epithelial (RPE) cells. Intracellular Ca2+ concentration ([Ca2+]i) of human RPE cells in primary culture was monitored using Fura-2. Cyclic adenosine monophosphate (cAMP) concentration was...
Topics
- Acetylcholine
- Adenosine
- Adenosine Triphosphate
- Adenylyl Cyclase Inhibitors
- Adenylyl Cyclases
- Adrenergic beta-Agonists
- Calcium
- Cells, Cultured
- Cyclic AMP
- Drug Synergism
- Epithelial Cells
- Humans
- Immunohistochemistry
- Isoproterenol