Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potentiation of ATP-induced Ca2+ mobilisation in human retinal pigment epithelial cells.

Experimental eye research - 1 Apr 2005

Collison David J, Tovell Victoria E, Coombes Laura J, Duncan George, Sanderson Julie

Abstract excerpt

Interaction of signalling pathways directs the functional output of many cells. This study investigated the consequences of activating adenosine and adrenergic receptors on ATP-induced Ca2+ responses in human retinal pigment epithelial (RPE) cells. Intracellular Ca2+ concentration ([Ca2+]i) of human RPE cells in primary culture was monitored using Fura-2. Cyclic adenosine monophosphate (cAMP) concentration was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Adenosine
Share to Adenylyl Cyclases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Adrenergic beta-Agonists

Share to Drug Synergism

Share to Isoproterenol

Share to Pigment Epithelium of Eye

Share to Vasodilator Agents

Source

Identifiers

PMID: 15781274
DOI: 10.1016/j.exer.2004.09.009

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potentiation of ATP-induced Ca2+ mobilisation in human retinal pigment epithelial cells.PMID 15781274Read ↗

ATP potentiates agrin-induced AChR aggregation in cultured myotubes: activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions.Semantic proximity Read ↗

Galphaq potentiation of adenylate cyclase type 9 activity through a Ca2+/calmodulin-dependent pathway.Semantic proximity Read ↗

Adenosine and its nucleotides activate wild-type and R117H CFTR through an A2B receptor-coupled pathway.Semantic proximity Read ↗

Stimulation of chloride secretion by P1 purinoceptor agonists in cystic fibrosis phenotype airway epithelial cell line CFPEo-.Semantic proximity Read ↗

Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle.Semantic proximity Read ↗

Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation.Semantic proximity Read ↗

Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.Semantic proximity Read ↗

cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts.Semantic proximity Read ↗

Adenosine and P2 receptors in PC12 cells. Genotypic, phenotypic and individual differences.Semantic proximity Read ↗

Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B.Semantic proximity Read ↗

Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils.Semantic proximity Read ↗

Extracellular ATP increases intracellular calcium in cultured adult Schwann cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.