Article
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils.
British journal of pharmacology - 1 Apr 2003
Idzko Marco, Panther Elisabeth, Bremer Hinrich C, Sorichter Stephan, Luttmann Werner, Virchow J Christian, Di Virgilio Francesco, Herouy Yared, Norgauer Johannes, Ferrari Davide
Abstract excerpt
1. Extracellular nucleotides are the focus of increasing attention for their role as extracellular mediators since they are released into the extracellular environment in a regulated manner and/or as a consequence of cell damage. 2. Here, we show that human eosinophils stimulated with different nucleotides release eosinophil cationic protein (ECP) and the chemokine interleukin 8 (IL-8), and that release of these...
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