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Article

Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.

The Journal of biological chemistry - 12 Mar 2004

Haidar Bassam, Denis Maxime, Marcil Michel, Krimbou Larbi, Genest Jacques

Abstract excerpt

It has been suggested that the signal transduction pathway initiated by apoA-I activates key proteins involved in cellular lipid efflux. We investigated apoA-I-mediated cAMP signaling in cultured human fibroblasts induced with (22R)-hydroxycholesterol and 9-cis-retinoic acid (stimulated cells). Treatment of stimulated fibroblasts with apoA-I for short periods of time (<or=45 min) increased ATP binding cassette A1...

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Source

Identifiers

PMID: 14701824
DOI: 10.1074/jbc.M313487200

Genes

ABCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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