Article
[Steroidogenesis in adrenal glands of young and adult female mice with hyperexpression of the Aguoti gene].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 May 2006
Iakovleva T V, Shevchenko A Iu, Makarova E N, Bazhan N M
Abstract excerpt
Dominant mutation Agouti yellow (AY) leads to ectopic overexpression of the Agouti gene and yellow coat color in mice. Furthermore, the mutation Ay increased adrenal response to emotional stress. The study assessed whether pleiotropic effect of the mutation Ay on adrenals function was dependent on sex and age. 3- and 15-week old female C57B1/6J mice of two agouti-genotypes: Ay/a (ectopic Agouti-gene...
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