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Article

[Pituitary-adrenal function in female mice with mutation Agouti yellow (A(y))].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 Nov 2004

Karkaeva N R, Iakovleva T V, Makarova E N, Shevchenko A Iu, Bazhan N M

Abstract excerpt

Agouti protein is a paracrine signaling factor modulating action of ACTH and alpha-MSH. Dominant mutation Ay causes ectopic, ubiquitous expression of Agouti protein in mice. It was shown that Ay mutation increased stress-induced hypothalamo-adrenal activity in male mice. There is a sex difference in the hypothalamo-pituitary-adrenal axis in rodents. The aim of this study was to test effects of ectopic...

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PMID: 15646207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Pituitary-adrenal function in female mice with mutation Agouti yellow (A(y))].PMID 15646207Read ↗

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Agouti yellow mutation increases adrenal response to ACTH in mice.Semantic proximity Read ↗

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Ectopic Agouti protein overexpression increases stimulated corticosterone production without effect on adenylate cyclase activity in mouse adrenal cells.Semantic proximity Read ↗

Effect of the agouti gene on the hypothalamic-hypophyseal-adrenal system in mice.Semantic proximity Read ↗

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