Article
[The effect of the "yellow" mutation at the mouse agouti locus on the hormonal profile of pregnancy and lactation].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 Nov 2009
Bazhan N M, Makarova E N
Abstract excerpt
The "yellow" mutation at the mouse agouti locus (A(y)/a-mice) results in obesity and type 2 diabetes. Maternal obesity in A(y)-mice impaired glucose tolerance in adult Agouti-negative offspring. Changes of hormone pattern during pregnancy and lactation are known to disregulate glucose metabolism in the adult progeny. The aim of the study was to assay blood levels of glucose, insulin, corticosterone and leptin...
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