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Article

Melanocortins and body weight regulation: glucocorticoids, Agouti-related protein and beyond.

European journal of pharmacology - 11 Jun 2011

Corander Marcus P, Coll Anthony P

Abstract excerpt

In the intervening three decades since Panksepp observed for the first time that centrally administered α-melanocyte stimulating hormone decreased food intake (Panksepp and Meeker, 1976), a wealth of data have accrued to firmly establish melanocortin signaling as a central regulator of food intake and fat mass. Advances in molecular biology have not only allowed detailed studies of spontaneously occurring obese...

Topics

Agouti-Related Protein
Animals
Body Weight
Dietary Fats
Glucocorticoids
Humans
Melanocortins
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21199644
DOI: 10.1016/j.ejphar.2010.10.103

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