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Article

Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line.

FEBS letters - 27 Apr 1992

Kelleher D, Long A

Abstract excerpt

In the human T-cell lymphoma line, HuT 78, proliferation and phorbol ester-induced growth arrest and differentiation were inhibited by the protein kinase C (PKC) inhibitor, staurosporine. By contrast, an alternative PKC inhibitor, H-7, inhibited proliferation but not phorbol ester-induced growth arrest. The cell line was found to contain both alpha and beta isoforms of PKC by Western blot techniques. A cell line,...

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Identifiers

PMID: 1577171
DOI: 10.1016/0014-5793(92)80264-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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