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Article

Differential responses of staurosporine on protein kinase C activity and proliferation in two murine neuroblastoma cell lines.

Cancer letters - 24 May 1999

Mohan D R, Nagarathna R, Krishna M, Jagtap J C, Shastry P

Abstract excerpt

We studied the effect of staurosporine (SSP), a broad-spectrum protein kinase inhibitor, on the levels of protein kinase C (PKC) activity and proliferation in two murine neuroblastoma cell lines, Neuro2a and its clone NB41A3. The PKC activity was examined in whole cell lysate, cytosolic and particulate fractions. A differential response to SSP treatment in the enzyme activity in whole cell lysate and particulate...

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PMID: 10395170
DOI: 10.1016/s0304-3835(99)00021-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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