Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characterization of human homologs of yeast MOB1

8 Sept 2009

Abstract excerpt

MOB (Mps one binder) was originally identified in yeast as a regulator of mitotic exit and cytokinesis, and was later identified as a tumor suppressor and a component of an emerging Hippo-LATS tumor suppressor pathway in Drosophila (D). So far, 7 human homologs of yeast MOB (hMOB1A, 1B, 2A, 2B, 2C, 3, 4) have been identified. Although hMOB1A/B has been extensively studied, the biological features of other hMOBs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Hippo pathway signaling and YAP/TAZ
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19739119
DOI: 10.1002/ijc.24878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterization of human homologs of yeast MOB1PMID 19739119Read ↗

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complexSemantic proximity Read ↗

MHO1, an evolutionarily conserved gene, is synthetic lethal with PLC1; Mho1p has a role in invasive growth.Semantic proximity Read ↗

Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the <i>Drosophila Hippo</i> PathwaySemantic proximity Read ↗

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.Semantic proximity Read ↗

The MPS1 Family of Protein KinasesSemantic proximity Read ↗

LATS tumor suppressor: A new governor of cellular homeostasisSemantic proximity Read ↗

Function and cancer genomics of FAT family genesSemantic proximity Read ↗

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.Semantic proximity Read ↗

hMOB2 deficiency impairs homologous recombination-mediated DNA repair and sensitises cancer cells to PARP inhibitorsSemantic proximity Read ↗

A systematic analysis of human CHMP protein interactions: Additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complexSemantic proximity Read ↗

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer)Semantic proximity Read ↗

An Oxysterol-Binding Protein Family Identified in the MouseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.