Article
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.
Cell - 23 Aug 2002
Tapon Nicolas, Harvey Kieran F, Bell Daphne W, Wahrer Doke C R, Schiripo Taryn A, Haber Daniel A, Hariharan Iswar K
Abstract excerpt
The number of cells in an organism is determined by regulating both cell proliferation and cell death. Relatively few mechanisms have been identified that can modulate both of these processes. In a screen for Drosophila mutations that result in tissue overgrowth, we identified salvador (sav), a g...
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