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Article

The Hippo/STE20 homolog SIK1 interacts with MOB1 to regulate cell proliferation and cell expansion in Arabidopsis.

Journal of experimental botany - 1 Mar 2016

Xiong Jie, Cui Xuefei, Yuan Xiangrong, Yu Xiulian, Sun Jialei, Gong Qingqiu

Abstract excerpt

Multicellular organisms co-ordinate cell proliferation and cell expansion to maintain organ growth. In animals, the Hippo tumor suppressor pathway is a master regulator of organ size. Central to this pathway is a kinase cascade composed of Hippo and Warts, and their activating partners Salvador and Mob1/Mats. In plants, the Mob1/Mats homolog MOB1A has been characterized as a regulator of cell proliferation and...

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Identifiers

PMID: 26685188
DOI: 10.1093/jxb/erv538

Genes

SIK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Hippo/STE20 homolog SIK1 interacts with MOB1 to regulate cell proliferation and cell expansion in Arabidopsis.PMID 26685188Read ↗

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.Semantic proximity Read ↗

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Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling.Semantic proximity Read ↗

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.Semantic proximity Read ↗

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.Semantic proximity Read ↗

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