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Article

A-Raf associates with and regulates platelet-derived growth factor receptor signalling.

Cellular signalling - 1 Jul 2005

Mahon Elizabeth S, Hawrysh Andrea D, Chagpar Ryaz B, Johnson Lindsey M, Anderson Deborah H

Abstract excerpt

Raf kinases are important intermediates in epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) mediated activation of the mitogen-activated protein kinase (MAPK) pathway. In this report, we show that the A-Raf kinase is associated with activated EGF receptor complexes and with PDGF receptor (PDGFR) complexes independent of prior PDGF treatment. The ability of A-Raf to associate with receptor...

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Source

Identifiers

PMID: 15763428
DOI: 10.1016/j.cellsig.2004.11.006

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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